N6-METHYLADENOSINE MODIFICATION OF HIV-1 RNA SUPPRESSES TYPE-I INTERFERON INDUCTION IN DIFFERENTIATED MONOCYTIC CELLS AND PRIMARY MACROPHAGES.

N6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages.

N6-methyladenosine (m6A) is a prevalent RNA modification that plays a key role in regulating eukaryotic cellular mRNA functions.RNA m6A modification is regulated by two groups of cellular proteins, writers and erasers that add or remove m6A, respectively.HIV-1 RNA contains m6A modifications that modulate viral infection and gene expression in CD4+

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Genre as diversity, and rhetorical mode as unity in language use

Current theorizing on genre within Systemic Functional Linguiscs (SFL) whip carbon magnum as well as other traditions of genre analysis have not paid much attention to the interrelationship between the notions of rhetorical mode and genre.In this paper I argue that rhetorical mode may be an important notion in genre studies and that it should thus

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The Effect of Seawater Used for Hydrodistillation on Essential Oil Yield and Composition of Oil-Bearing Rose (Rosa damascena Mill.)

Oil-bearing rose (Rosa damascena Mill.) is the most important rose species having a high-value volatile oil, used in the fragrance and cosmetic industries.Epidermal cells of the flower petals are the main essential oil source.During the boiling process of hydrodistillation, the essential oil in the cells diffuses through the cell walls by means of

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Fast Timing Techniques in FLIM Applications

Fluorescence lifetime imaging (FLIM) is increasingly used in many scientific disciplines, including biological and medical research, materials science and chemistry.The fluorescence label is not only used to j&d manufacturing website indicate its location, but also to probe its immediate environment, via its fluorescence lifetime.This allows FLIM t

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